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What Are The Differences Between Neurotoxins (Botox) and Dermal Fillers?

  • Selena Fu, MD
  • May 20
  • 3 min read

by Dr. Selena Fu, Oculoplastic Surgeon, Owner of RSVP Med Spa and Hive Overland Park member


Neurotoxins vs dermal fillers

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If you have ever thought about treating those pesky wrinkles and fine lines but were unsure of the options, here is a little scoop on the difference between neurotoxins like Botox and dermal fillers. Both treatments are non-surgical, temporary and only involve a quick injection.


The Whys: Botox vs. Dermal Fillers


Neurotoxin (Botox):

Mechanism of Action:

  • Neurotoxin, such as Botox, Dysport, Jeuveau and Daxxify are derived from the bacterium Clostridium botulinum. It works by temporarily blocking nerve signals in the muscles where it's injected. This targeted muscle relaxation is what makes it highly effective in reducing dynamic wrinkles caused by repetitive facial expressions.

Common Uses:

  • Neurotoxin is renowned for its proficiency in addressing dynamic wrinkles, such as crow's feet, forehead lines, and frown lines. By inhibiting muscle movement, it provides a smoother and more youthful appearance to the treated areas.

Duration of Results:

  • The effects of Neurotoxin are not permanent, typically lasting around three to four months. Regular maintenance appointments can sustain the desired results, allowing individuals to enjoy ongoing benefits.


Dermal Fillers:

Mechanism of Action:

  • Dermal fillers, on the other hand, work by adding volume beneath the skin. Comprising substances like hyaluronic acid, a naturally occurring compound in the body, dermal fillers restore lost volume, plump sagging skin, and soften facial contours.


Common Uses:

  • Dermal fillers excel in addressing static wrinkles, which are present even when the face is at rest. They are also used to enhance facial features, restore facial symmetry, and volumize areas like the temple hollows, cheeks, smile lines, lips, ear lobes, and hands.


Duration of Results:

  • The longevity of dermal filler results varies depending on the specific filler used. While some may last six months, others, especially those with more robust formulations, can offer results for up to one to two years.


The Art of Personalization

No two faces are alike and your provider will assess the unique characteristics of your face, discuss your aesthetic goals, and formulate a customized treatment plan that may involve Botox, dermal fillers, or a combination of both.


Targeted Application:

  • Botox and dermal fillers are strategically applied to different areas of the face based on their mechanisms of action. Botox is ideal for dynamic wrinkles in motion-prone areas, while dermal fillers are chosen to add volume and soften static wrinkles.

Achieving Synergy:

  • Combining Botox with dermal fillers can often yield a synergistic effect. The muscle relaxation from Botox and the volumizing effect of fillers can work together harmoniously to achieve comprehensive facial rejuvenation. This combination approach is carefully tailored to enhance overall facial aesthetics.


Common Misconceptions:

Neurotoxin / Botox "Freezes" the Face:

  • While Botox temporarily relaxes targeted muscles, the goal is to soften wrinkles, not immobilize the face completely. A skilled practitioner ensures precise application to maintain natural facial expressions.

Fillers Always Look Overdone:

  • The key to achieving natural-looking results with fillers lies in the expertise of the injector. It is an art! Ask your practitioner for a conservative approach, ensuring that enhancements are subtle and give you the result you are looking for.



If you are interested in learning more, RSVP Med Spa can help. They offer a comprehensive range of cosmetic procedures. These include eyelid surgery, facial rejuvenation, and non-surgical options like laser treatments, skincare regimens and body contouring — all aimed at enhancing natural beauty with precision and care.


Selena Fu, MD

SELENA FU, MD

Oculoplastic Surgeon

913-387-1104

13300 Metcalf Avenue, Overland Park, KS 66213


Dr. Fu is board-certified by the American Board of Ophthalmology and a proud member of the American Academy of Ophthalmology and the American Academy of Cosmetic Surgery.





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